BDBM50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta

SMILES OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1

InChI Key InChIKey=NJMYODHXAKYRHW-BLLMUTORSA-N

Data  62 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50026957   

TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
In DepthDetails PubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  3.16nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  18nMAssay Description:Binding affinity of compound towards Dopamine receptor D1 using [3H]SCH-23390 (0.5 nM) ligand in striatum bovine was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  38nMAssay Description:Binding affinity which represents concentration giving half-maximal inhibition of [3H]SCH-23390 (Dopamine receptor D1) binding to rat tissue homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  474nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  474nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  721nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  907nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50026957((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
Affinity DataKi:  8.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed